LabTube Meets John Draper, Aberystwyth University

Dynamic Light Scattering (DLS) is a technique classically used for measuring the size of particles typically in the sub-micron region, dispersed in a liquid. The sensitivity of some modern systems is such that it can also now be used to measure the size of macromolecules in solution.

Scientists from the University of Bristol, CNRS and Imophoron Ltd worked with the computer technology giant Oracle to develop a new kind of vaccine that needs no refrigeration. They used synthetic biology, cryo-electron microscopy and high-performance cloud computing to produce a candidate vaccine against the mosquito-borne chikungunya virus. Their findings could revolutionise the way vaccines are designed, developed and stored.

Can we make drugs that not only break/inhibit interactions between a protein and a ligand, but rather bestow new functionality? Nicolas Thomä explores molecular glue drugs, and their potential to make much needed medicines that were previously out of reach.