PI3K - Akt Upstream Signaling from Cell Signaling Technology, Inc.

Stimulation of membrane receptors by growth factors or cytokines results in signal transduction leading to the activation of the kinase Akt,. Active Akt then can activate (phosphorylate) a large number of downstream proteins (substrates) that can be grouped by their effects on protein synthesis, survival, proliferation, glucose metabolism, neuroscience and other cellular effects. This presentation discusses the details of upstream signaling involved in Akt activation. Visit http://www.cellsignal.com to see antibodies for the study of Akt Signaling.