We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Advertisement

Monitoring Dynamic Interactions of Tumor Cells with Tissue and Immune Cells in a Lab-on-a-Chip

Video   Dec 01, 2015

 

A complementary cell analysis method has been developed to assess the dynamic interactions of tumor cells with resident tissue and immune cells using optical light scattering and impedance spectroscopy to shed light on tumor cell behavior. The combination of electroanalytical and optical biosensing technologies integrated in a lab-on-a-chip allows for continuous, label-free and non-invasive probing of dynamic cell-to-cell interactions between adherent and non-adherent co-cultures, thus providing real-time insights into tumor cell responses under physiologically relevant conditions. While the study of adherent co-cultures is important for the understanding and suppression of tumor invasion, the analysis of tumor cell interactions with non-adherent immune cells plays a vital role in cancer immunotherapy research. For the first time the direct cell-to-cell interactions of tumor cells with bead-activated primary T cells were continuously assessed using an effector cell to target cell ratio of 10:1.

 
 
 
Advertisement
 

Recommended Videos

What Are Exosomes?

Video

What are exosomes? Find out about these tiny-but-potent circulating microvesicles that participate in cellular communication.

WATCH NOW

Microfluidics Adventures Part 3: Microfluidic Chips

Video

In the third and final series of Microfluidics Adventures by The Lutetium Project, we show you microfluidic chips as you've never seen them before. Let’s mix some microdroplets!

WATCH NOW

Microfluidics Adventures Part 2: How To Build a Miniature World

Video

In part two of "Microfluidics Adventures", brought to you by the Lutetium Project, Marie Boulez talks us through the major components of a microfluidics system, and shows us how to piece everything together.

WATCH NOW

 

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE