Molecular imaging is increasingly being used to support decision-making in early-stage drug development, particularly in the CNS. Providing invaluable information on the so-called ‘three pillars of drug survival’, namely tissue delivery, target engagement and pharmacological effect, it can be seen as a kind of precision pharmacology However, a lack of appreciation of when and how to use imaging and a lack of suitable tools means imaging is often an afterthought and employed in a post-mortem of drug failure. Timely development of imaging biomarkers will ensure the full translational value of this technology can be realised
Parallel Tracking i-biomarkerT Development with Drug Development for Maximum Benefit
Video Jul 07, 2015
Aerogels are the world's lightest (least dense) solids. They are also excellent thermal insulators and have been used in numerous Mars missions and the Stardust comet particle-return mission. The focus of this video is silica aerogels, though graphene aerogels are now technically the lightest.