Size Matters: Insights From a Swine Model of Pulmonary Hypertension

Name: Size Matters: Insights From a Swine Model of Pulmonary Hypertension
Uploaded: 2024-12-06
Description: In this episode of Science Spotlight, Dr Moreira-Costa presents her research on a simplified large animal model that successfully induces a severe cardiovascular phenotype. This approach could drive advancements in diagnostics and therapeutics.

Video

Published: December 6, 2024

Bree Foster, PhD

Chronic thromboembolic pulmonary hypertension (CTEPH) is a life-threatening condition caused by persistent clots blocking the pulmonary arteries. Despite ongoing research, the underlying mechanisms of CTEPH remain unclear.

Existing animal models used to study CTEPH require complex protocols and often fail to replicate the severe pulmonary artery pressures seen in humans.

In this episode of Science Spotlight, Dr Moreira-Costa presents her research on a simplified large animal model that successfully induces a CTEPH phenotype. This approach has the potential to drive advancements in diagnostics and therapeutic strategies for this life-threatening condition.

Watch this episode to understand:

The limitations of current CTEPH models and the need for innovation
How a simplified large animal model replicates severe CTEPH with clinical relevance
Potential applications for improving diagnostic tools and developing targeted treatments

Meet the Author

Bree Foster, PhD

Science Writer

Bree holds both a BSc and PhD in Genetics from the University of Liverpool. After completing her studies, she spent two years as a science writer at an agency. Eager to broaden her expertise, she joined Technology Networks as a science writer in 2024. In her current role, she is responsible for producing custom written content and contributing to the development of digital media.