We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Targeting Tumors: Challenges of Antibody-Drug Conjugates

Video   Jun 12, 2018 | Nature Video, YouTube

 

Treating cancer requires aggressive but targeted therapy. Some cancer drugs are too toxic because they damage healthy cells as well as tumor cells. So researchers are trying to develop ways to make sure drugs only target the right cells.

One solution is to attach drugs to antibodies specific to a protein expressed on tumor cells. These drugs are called antibody-drug conjugates (ADCs).

More than two dozen ADCs are currently being used in the clinic to treat diseases like Hodgkin's lymphoma and breast cancer, and researchers are developing many more. But it's taken decades to find the right combination of drug, antibody target and linker, and then make sure the right amount of ADC hits the tumor. 


 
More Information
 
 
 

Recommended Videos

Dr. Lina R. Nih Discusses Her Novel Approach to Brain Vasculature Regeneration

Video

Xandrina and Adam speak with Dr. Lina Nih to find out about her novel hydrogel approach to brain tissue repair following Stroke

WATCH NOW

How Komodo Dragon Blood May Save Lives

Video

Komodo dragons, the largest lizards on earth, carry antimicrobial peptides in their blood as a defense against infections. Researchers at George Mason University used these peptides to treat wound infections in mice and hope we will be able to develop new antibiotics based on these chemicals.

WATCH NOW

On the Pathway to Discovery, All Signals are Clear

Video

What if you could get high quality results without the hassle? Our wide range of assay solutions makes it easier to take an orthogonal approach to your cell-based assays, glean more biologically relevant information, and get to breakthroughs faster.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Biopharma Cancer Research Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE