We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Targeting Tumors: Challenges of Antibody-Drug Conjugates

Video   Jun 12, 2018 | Nature Video, YouTube

 

Treating cancer requires aggressive but targeted therapy. Some cancer drugs are too toxic because they damage healthy cells as well as tumor cells. So researchers are trying to develop ways to make sure drugs only target the right cells.

One solution is to attach drugs to antibodies specific to a protein expressed on tumor cells. These drugs are called antibody-drug conjugates (ADCs).

More than two dozen ADCs are currently being used in the clinic to treat diseases like Hodgkin's lymphoma and breast cancer, and researchers are developing many more. But it's taken decades to find the right combination of drug, antibody target and linker, and then make sure the right amount of ADC hits the tumor. 


 
More Information
 
 
 

Recommended Videos

Bacterial DNA Jiggling Motion Halted Before Cell Death

Video

Watch how the jiggling motion of bacterial DNA stops when a natural antimicrobial peptide permeates the E. coli membrane. This novel mechanism helps explain why bacteria develop resistance very slowly and may inform the design of new antimicrobial agents.

WATCH NOW

Top Science Stories of 2018

Video

We have seen some amazing scientific breakthroughs in 2018. Here is a selection of our favorites.

WATCH NOW

The Science of Christmas

Video

Does Rudolph's nose really glow? Why doesn't anybody see Santa deliver presents? Modern science can help you explain the mysteries of Santa to your kids!

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Biopharma Cancer Research Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE