Discernment of rare alleles in circulating free DNA (cfDNA) may be a useful method for detecting the presence of new or recurring cancer long before it becomes symptomatic and, perhaps, when it is more treatable. Unfortunately the false-positive rate of current methods reduce specificity to an unacceptable level at allele frequencies of less than ~0.5%.
Tissue and cfDNA Rare Alleles How Low Can We Go
Video Apr 28, 2015
Modern machine learning is great for helping scientists sort through huge data sets. But it’s less useful for things that require inference or reasoning – both vital to the scientific process. One group of scientists are now trying to fix this problem with a new kind of machine learning. This new approach aims to find the underlying algorithmic models that interact and generate data, to help scientists uncover the dynamics of cause and effect.WATCH NOW