Translation of Omic Data into Personalised Oncology Tools The Challenge and the Reward

About the Speaker

Prof. Gallagher is currently the Chief Scientific Officer (CSO) at OncoMark. A major focus of Prof. Gallagher’s research work is the identification and validation of candidate biomarkers of breast cancer and melanoma, with particular emphasis on translation of transcriptomic and proteomic datasets into clinically relevant assays. In addition, his team (the Cancer Biology and Therapeutics Lab; www.cbtlab.ie) investigates the functional relevance of candidate tumour progression-associated genes at both in vitro and in vivo levels, as well as engages in preclinical evaluation of novel anti-cancer agents.Abstract
This presentation will cover how bottlenecks in the validation of candidate tumour progression-related biomarkers can be overcome. In particular, the use of tissue microarray technology and digital pathology will be highlighted. In addition, a novel mechanistically anchored biomarker panel that outcompetes current prognostic classifiers in breast cancer will be introduced for the first time.