A flexible, fast and cost-effective fabrication concept is investigated to meet such demands. Unibody lab-on-a-chip (ULOC) devices are conceived around a single 3D printed monolithic structure that hosts all the complementary functionalities for sample handling, chemical interfacing and detection coupling. Prototypes can be produced in less than 30min for about 0.5 US$/device, and in this presentation their capabilities and potential are examined.