3D RNA Imaging of Mouse Whole Brain at Single-Cell Resolution
Join this webinar to learn about TRIC-DISCO, a new pipeline for whole-brain 3D imaging of RNA spatial distributions. This innovative technique controls penetration of DNA probes for in situ hybridization to achieve uniform whole-brain staining. By using TRIC, in situ hybridization signals are maintained during clearing by DISCO, producing highly transparent tissues. The workflow eliminates the need for strict RNase-free environments and enables simple and robust whole-brain 3D imaging of transcriptional signatures, cell identity markers and noncoding RNAs at single-cell resolution throughout the entire brain. Don't miss this opportunity to learn about this groundbreaking technology and how it can impact your research.
Attend this webinar to:
- Learn about the limitations of current spatial analysis methods for RNA in whole-brain samples
- Get to know TRIC-DISCO, a new pipeline enabling 3D imaging of spatial distributions of RNA in whole adult mouse brains
- Discover the significant impact of TRIC-DISCO on the neuroscience field and beyond