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4D-Lipidomics™: Searching for the Fountain of Youth

4D-Lipidomics™: Searching for the Fountain of Youth content piece image

To confidently characterize complex lipidomes of whole organisms, researchers require comprehensive MS/MS coverage of detected lipids. Compared to conventional analyses, the timsTOF Pro, used with Parallel Accumulation Serial Fragmentation (PASEF) acquisition mode, acquires MS/MS spectra with uncompromised sensitivity and resolution.

This webinar will demonstrate Bruker’s fully integrated lipidomics workflow in MetaboScape and outline how novel 4D-lipidomics tools has been used to gain a better understanding of how a sphingolipid mutation in the C. elegans relates to an increased lifespan – or in other words, the fountain of youth.

Attend the webinars to discover how to: 

  • Increase confidence in lipid annotation using rule-based annotation to reduce false positives
  • Increase the number of MS/MS in a single run to allow for a higher level of chain composition annotation
  • Automatically record reproducible CCS for all lipids within a sample to further add confidence
  • See how new visualisation tools, including Kendrick mass defect plots, can save time and simplify your research
Dr Ansgar Korf
Dr Ansgar Korf
Software Engineer, Bruker Daltonik GmbH
Dr Michael Witting
Dr Michael Witting
Deputy Head Metabolomics and Proteomics Core, Executive Manager Metabolomics Helmholtz Zentrum München