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Drug Discovery

Discover New Ways To Increase Your Throughput for Metabolic Stability Assays

Adsorption, distribution, metabolism and excretion (ADME) profiling is used to determine the properties of drug candidates. Modern drug discovery environments depend on the accuracy and precision of results from ADME studies to select new targets with a high potential for clinical success.


However, as technology advances, the size of compound libraries increases. Once a compound shows an affinity for a target, understanding the ADME profile of a drug in vitro can reduce attrition rates in the drug development process.

Acoustic ejection mass spectrometry (AEMS) has a significantly higher throughput than traditional LC-MS approaches due to the rapid sampling and flow injection analysis enabled by a high-sensitivity mass spectrometer. In the webinar, we discuss a suite of metabolic stability assays developed using an AEMS system.


Attend this webinar to: 

  • Learn about how the Echo® MS system can be used in drug discovery 
  • Hear about the advantages of AEMS 
  • Discover the fundamentals of Echo® MS operation and how it can benefit your research
Speaker
Dr. Jacob W. McCabe
Dr. Jacob W. McCabe
Senior Scientist Echo® MS Center of Excellence, SCIEX
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