Every Breath You Take: Predicting Inhaled Drug ADME Using Lung-on-a-Chip
The administration of drugs via inhalation into the lungs is superior to many other methods of delivery because our lungs provide a large surface area for absorption, access to the whole blood volume and comparatively little metabolic activity. Currently, there are limited in vitro models in which the absorption and permeability of drugs across the lung and into systemic circulation can be precisely measured.
In this webinar, Dr. Emily Richardson will describe novel lung-on-a-chip (LOAC), otherwise known as lung microphysiolological system, models of the alveoli and bronchi which can be used to accurately predict drug pharmacokinetics, allowing for more rapid, precise and cost-effective analysis of compounds.
Attend this webinar to:
- Understand the advantages and disadvantages of oral drug inhalation
- Discover how to culture LOAC models using CN Bio’s PhysioMimix™ OOC
- Learn how LOAC models accurately mimic the human lung
- Ascertain LOAC’s ability to predict the permeability and absorption of inhaled medication