Exploring How Alternative Splicing and Gene Isoforms Influence Disease

Alternative splicing is crucial for eukaryotic gene expression and influences protein function and regulation, with mis-splicing linked to numerous diseases. In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect and quantify full-length gene isoforms. She will also illustrate how this research could pave the way for new therapeutic targets to treat kidney diseases. Additionally, Christophe Fleury will explore the use of long nanopore reads for both bulk and single-cell RNA sequencing (scRNA-seq) studies, highlighting how it can maximize the recovery of biological information and drive new discoveries. Attend this webinar to: Explore the role of alternative splicing in disease progression Learn how to accurately detect and quantify full-length gene isoforms Discover how long nanopore reads can be used for bulk and single-cell RNA sequencing