
Maximizing Translational Relevance in In Vivo Pharmacology
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In vivo pharmacology remains the gold standard for evaluating the efficacy and pharmacodynamics of therapeutic candidates in preclinical development.
Selecting precise, clinically relevant animal models is critical for generating high-quality data and ensuring a seamless transition to clinical trials.
In this webinar, our expert speaker will discuss how to select non-human primate and murine models to maximize translational relevance in in vivo pharmacology for therapeutic candidates, particularly modalities such as antibody–drug conjugates, T-cell engagers and Fc-engineered antibodies.
- Rational study design to align preclinical models with human disease biology
- Key considerations for selecting optimal species and models that maximize translational relevance of pharmacodynamic, pharmacokinetic and efficacy analysis
- How to interpret data to extract actionable insights from complex pharmacodynamic and histological datasets
- Proactive troubleshooting approaches to overcome preclinical challenges and accelerate timelines

