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3D illustration of monoclonal antibodies (mAbs) binding to target antigens on cell surfaces, showcasing molecular interactions

Overcome Key Challenges in Complex mAb Purification


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The rise of novel monoclonal antibody (mAb) formats has not only transformed the therapeutic landscape but also introduced new purification challenges. 


From bispecific antibodies to antibody–drug conjugates, these diverse formats come with unique structural properties that complicate purification efforts. Variations in size, charge and hydrophobicity require specialized approaches to maintain efficiency and product integrity.


In this webinar, experienced panelists discuss the key challenges in complex mAb purification and offer practical solutions to optimize downstream processing systems for even the most complex mAb formats.


Watch this webinar to explore:

  • Effective affinity capture for challenging mAb formats
  • Strategies for removing impurities while maintaining integrity
  • Best practices for resin selection and downstream system design
Speakers
A picture of Brian O'Mara
Brian O'Mara
VP of Process Sciences
Scorpius BioManufacturing
A picture of Angela Lewandowski, PhD
Angela Lewandowski, PhD
Senior Director, Downstream Bioprocess Development
Bristol Myers Squibb
A picture of Buzz Lobbezoo
Buzz Lobbezoo
Senior Field Application Specialist
Thermo Fisher Scientific
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