Beyond Next Generation DNA Sequencing Single Molecule Real Time (SMRT™) Technology
White Paper Jan 31, 2012
Pacific Biosciences Single Molecule Real Time (SMRT) DNA sequencing technology enables, for the first time, observation of natural DNA synthesis by a DNA polymerase as it occurs. The approach is based on “eavesdropping” on a single DNA polymerase molecule working in a continuous, processive manner. Distinguished by its long reads, fast time to result, more informative data, and lower overall costs, SMRT DNA sequencing promises to be a transformative technology that will enable a new paradigm in genomic analysis.