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Stellaris RNA FISH: Detection, Localization, and Quantification of mRNA at the Cellular Level

Abstract

Presented here is a new method for in situ RNA detection, the Stellaris™ FISH technology, which enables simultaneous detection, localization, and quantification of individual RNA molecules at the cellular level. This technique provides a high degree of specificity and sensitivity, is ideal for applications that analyze transcription site activity, protein- RNA interactions and mRNA translocation events, and holds promise for future diagnostic applications.