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Latest Application Notes

Application Note

Get a High-Resolution View of Your Lipid Nanoparticles

Lipid nanoparticles (LNP) play a key role in effectively protecting and transporting mRNA to target cells in mRNA-based vaccines and therapeutics. To ensure the quality and safety of LNP, lipid components and associated impurities/degradants need to be carefully characterized in raw materials and formulation.
Application Note

Where Do We Go From Here: A Reflection of COVID-19

Download this app note to explore various solutions designed to improve COVID-19 detection and the development of vaccines and therapeutics.
Application Note

Analysis of Genotoxic Nitrosamines in Losartan

Download this app note to discover a system that demonstrates good chromatographic separation of nitrosamine compounds and provides enhanced sensitivity.
Application Note

Shotgun Proteomics for Unbiased Quantification

Shotgun proteomics has the capacity to deliver in-depth information on the identification, the relative amount, and the modification patterns of ever larger fraction of the proteins present in a sample. This has made it an essential approach in most biological research areas.
Application Note

Greater Precision for Transformative Drug Discovery

Target identification and characterization are key challenges in drug discovery and begin with identifying the function of a possible therapeutic target and its role in the disease.
Application Note

Comprehending COVID-19: Peptide Mapping of the SARS-CoV-2 Spike Protein

The SARS-CoV-2 spike protein has rightly garnered attention as a leading candidate for protein-based vaccines for COVID-19. Multiple studies have shown that neutralizing antibodies bind to the spike protein at both peptide and peptidoglycan epitopes.
Application Note

The Analysis of Pharmaceuticals Using Dual Injection (U)HPLC

Many people pursue ideas of “efficiency” as an ideal for daily life — ideas include how many tasks we can accomplish in a short time frame and how we can minimize our impact on the environment. The same can be true with high performance liquid chromatography (HPLC).
Application Note

Maintaining the Health and Viability of Cells

Cell culture can be a challenging process because cells are influenced by many factors including how they are physically handled and the labware used to seed and feed cultures.
Application Note

Improve Recovery of Critical Protein Samples

Protein loss during sample preparation can be an obstacle to reliable product quantitation in all biopharmaceutical settings. Samples are often prepared from feedstocks containing insoluble particles and therefore require a solid-liquid separation before analysis to protect analytical instruments.
Application Note

Collaboration Delivers Pharma Efficiencies, Data Compliance and Weighing Excellence

Time is a precious commodity and with ever-increasing regulatory scrutiny, pharmaceutical laboratories are always on the lookout for simple solutions to make their routine tasks easier. Here, we speak with experts to find out how they helping scientists weigh samples in the most efficient yet trusted way to date.
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